it depends on how ventilated the room is, which essences are used, which quantity, and so on...
I do diffuse eucalyptus and tea-tree oil a few hours a day without adverse effect, but I have an ultrasonic diffuser set to the minimum and it would use less than 0.2ml a day were it to be in function all day long.
A sure thing though, keep the diffuser as far away as possible from th cage and make sure the gliders cannot enter in contact with the oil.