Un-neutered males just smell more as a rule but try not to clean everything at once. I clean pouches/ fabrics including cage covers every 2-3 weeks, wipe inside bars every week, and I use the tractor supply pellets and change my 3 neutered males drop pan once a month & the 5 girls pan every 2-3 weeks. I wash with only vinegar and hot water and rinse with just hot water (cuts the vinegar smell). I also buy eucalyptus from eucproducts and that just naturally smells amazing and the babies love it. I also have my cages covered all around except front and those trap a lot of the smell. In the winter I have to wash the bottom racks in my shower but during nice weather I hose my cages off about once a month.