We have three cats ourselves but they have never tried anything with the suggies. Even when we lost the suggies once and found them safe and sound the next morning with three playful cats in the house. When we first got our suggies though, we were a bit concerned, but they basically ignore each other. Once we had the suggies and a cat in the same room, ready to intervene if anything happened and even when the sugar glider jumped all over the room, the cat watched it for a few minutes before completely ignoring it! Maybe our cats are just lazy (although they chase frogs and insects) but we haven't had a problem so far.