The holes in the mesh are about 1/3 inch or less, and my glider can't eaven fit their head's through the holes.
Yes, my glider's still use the restroom while they run around and play, but I've had quite a bit of progress getting them to go into the huge litter tray at the bottom of the cage. I've heard that some glider's don'r care for the bottom of the cage, however my glider's love to carry their food to the bottom and eat it there.
I'm not really using a "litter", I just lined the tray with about an inch of aspen shavings. (Which my vet says is the best for glider's next to newspaper.)
My glider's LOVE papaya, and rather then using it as dinner I use it as a treat. Everytime they go to the restroom in the tray, I give them a little bit' of papaya, and they've actually made quite a point by going to the restroom in the tray before I come to take them out of their cage.